As we head out of February and into March, we celebrated the resilience of our colleagues from diverse backgrounds during Black History Month and continue to promote the accessibility to science and STEM careers. There were a couple really important dates to recognize girls and women in February as well, with the National Girls & Women in Sports Day on the first day of the month, followed by the International Day of Women and Girls in Science on February 11. And now in March, we have the entire month to celebrate the contributions of women throughout our history. To kick off Women's History Month, I wanted to take a look at some of the most accomplished women scientists that advanced our knowledge to new heights while overcoming societal pressures and prejudice.

The last day of February marks a hopeful end to winter and a transition in the sporting world as well, but is also important in society as a day to recognize and raise awareness for rare diseases. Known as Rare Disease Day, the goal is this observance is to remind humanity that just because a disease is not prevalent or has as much research dedicated to it does not make it any less important, as certain individuals obviously suffer from these rare diseases and deserve accessibility to treatment and hopefully a cure. While it makes sense that more funding is funneled to cancer and neurology research since it affects so many more people, performing research in these comparatively uncommon maladies could offer insight into their diseases that get most of the research dollars.

When living in Chicago, we would often get off on the 31st Street exit on Lakeshore Drive, and at the time there was a sign pointing out some parking areas for McCormick Place. I recall specifically that two of those were labeled "E2" and "E3" and being the gigantic nerd that I am, thought immediately of ubiquitin. Since it is found in every type of cell in all eukaryotic cells, the protein is appropriately named. Check out the cool ribbon model I made of ubiquitin for my students once upon a time, and then let's take a look at ubiquitin's functions in living organisms and how it contributes to health and disease.

As I march slowly toward the twilight of my life, ever more I wake up with aches and pains and can hear the sounds of popping bubble wrap or Rice Krispies drowning in milk every time I make any major movements. Everyone deals with the realization of their own mortality in different ways. Some decide to finally climb Mount Everest or go skydiving. For me, I decided to look into the research behind cellular aging, and how we can make the most of our later years with the power of knowledge and biomedical science. This does remind me of that one episode of Star Trek where Jake and Nog have to get stuff for a mad scientist's cellular regeneration and entertainment chamber, which is supposed to restore the cells to a younger state and keep them from being literally bored to death. If you consider some of the treatments and technology being implemented or proposed these days, it almost seems like Star Trek has inspired yet another advancement beyond just cell phones and Alexa.

We’ve all been there…the experiment didn’t work for the 87^th time, and the feeling of dread and impostor syndrome surrounds the mind as the seminar or thesis committee meeting looms. It’s easy to dwell on everything that isn’t working right at that moment, but there are scientific discoveries to be made, and someone has to do it, and it might as well be you! That’s easier said than done, but with the proper support mechanisms and some confidence boosts, your goals will be achievable.

Like many of you out there, I used to pass the incubation periods for my experiments by scouring YouTube for videos, both of the educational and entertaining variety. While the bulk of this was admittedly cat and animal videos and human misfortunes (that normally did not result in debilitating injuries or death, mind you), I did prefer the channels that were a combination of educational and entertaining, which is a philosophy I adopted as a teacher and mentor. So today, I'd like to share some of my favorite channels that might help you de-stress from a hard day at work, and also probably teach you something! You can click the headers to go to their main channel as well as check out the example videos.