Epidermal growth factor receptor (EGFR, also known as ErbB-1 or HER1) is a member of the ErbB family. This family includes four tyrosine receptor kinases: HER1 (ErbB1, EGFR), HER2 (ErbB2, NEU), HER3 (ErbB3), and HER4 (ErbB4). The ErbB family plays an important regulatory role in the process of cell physiology.
EGFR is distributed along the surface of cells including mammalian epithelial cells, fibroblasts, glial cells, keratinocytes, and more. The EGFR signaling pathway plays an important role in physiological processes such as cell growth, proliferation and differentiation. The loss of function in tyrosine kinases such as EGFR, or the abnormal activity/cell localization of key factors in related signaling pathways can cause tumor, diabetes, immunodeficiency and cardiovascular diseases.
KO-validated EGFR Antibody
Phosphorylated EGFR Antibody Duos
ABclonal also offers phosphorylated EGFR antibody duos that include phospho-specific andibodies and the KO-validated EGFR total protein antibody.