---
title: Endoplasmic Reticulum Marker
description: Organelle marker antibodies can be used to observe the morphological structure of organelles and understanding the subcellular localization of proteins.
image: https://blog.abclonal.com/hubfs/endoplasmic%20reticulum-01.png
---
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# Endoplasmic Reticulum Marker
[](https://blog.abclonal.com/blog/author/panyue-penny-hao)
[Panyue (Penny) Hao](https://blog.abclonal.com/blog/author/panyue-penny-hao)
Oct 30, 2018 9:43:46 PM
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Organelle marker antibodies are common tools in cell biology research. They can be used with immunofluorescence technology to observe the morphological structure of intracellular membrane-bound organelles and for understanding the subcellular localization of proteins. In turn, they help to explore the biological functions/role of organelle proteins in normal or disease models. These markers can also be used in Western blot (WB) experiments examining organelle extracts, as well as providing a positive control to determine whether the organelle is successfully extracted.
We focus today on the endoplasmic reticulum (ER) markers. The ER is a network of membrane-bound organelles that are the initial destination for proteins that are targeted for other organelles, the plasma membrane, or are to be secreted outside the cell. Proper ER function includes accepting the nascent protein as it is being translated by ribosomes, and ensuring that the protein is properly folded so it does not lead to accumulation of unusable cellular cargo. Disruptions in ER or the unfolded protein response can lead to cell death or various disease states such as cancer or neurodegenerative disorders.
ABclonal provides many antibody products for the study of ER and Golgi markers, as well as exosome markers. Please read our [blog on the vesicular transport system](https://blog.abclonal.com/blog/traffic-management-the-indispensable-vesicular-transport-system) and its role in cellular homeostasis, and check out some of our ER marker antibodies below. We are honored to be part of your journey to better understanding vesicular transport and the fight against human diseases!
## HSPA5 Polyclonal Antibody
[](https://abclonal.com/catalog-antibodies/HSPA5PolyclonalAntibody/A0241)[](https://abclonal.com/catalog-antibodies/HSPA5PolyclonalAntibody/A0241)
[](https://cta-redirect.hubspot.com/cta/redirect/2617944/c9dddb7d-690a-4b6f-bb58-b01b1e356306)
## CALR Polyclonal Antibody
[](https://abclonal.com/catalog-antibodies/CALRPolyclonalAntibody/A1066)
[](https://cta-redirect.hubspot.com/cta/redirect/2617944/bc81cf9b-8979-46a1-85aa-2f7f4d86f27e)
Tags: [ABclonal News](https://blog.abclonal.com/blog/topic/abclonal-news), [Organelle Marker](https://blog.abclonal.com/blog/topic/organelle-marker), [Featured Product Weekly](https://blog.abclonal.com/blog/topic/featured-product-weekly)
### [Panyue (Penny) Hao](https://blog.abclonal.com/blog/author/panyue-penny-hao)
Content creator, knowledge craver, all-around food fanatic thriving to survive in the fascinating yet uncharted world of biology.
## Related Posts
[](https://blog.abclonal.com/blog/golgi-apparatus-markers)
[Golgi Apparatus Markers](https://blog.abclonal.com/blog/golgi-apparatus-markers)
[](https://blog.abclonal.com/blog/featured-product-weekly-er-and-nuclear-membrane-markers)
[Featured Product Weekly: ER and Nuclear Membrane Markers](https://blog.abclonal.com/blog/featured-product-weekly-er-and-nuclear-membrane-markers)
[](https://blog.abclonal.com/blog/genome-research-features-epigenetic-antibodies-from-abclonal-technology)
[Genome Research Features ABclonal's Epigenetic Target Antibodies](https://blog.abclonal.com/blog/genome-research-features-epigenetic-antibodies-from-abclonal-technology)
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