--- title: "Featured Product Weekly: Lamin Antibody" description: "ABclonal Technology features lamin antibodies: involved in apoptosis, associated with neurological diseases, cell cycles, and mitoses." image: https://blog.abclonal.com/hubfs/Apoptosis%20Nuclear%20Lamina.png --- [![](https://img.abclonal.com/abclonal/Public/Images/25121homepage-logo.png)](https://blog.abclonal.com/) [\[fa icon="user"\]](https://abclonal.com/user/login) [\[fa icon="shopping-cart"\]](https://abclonal.com/shoppingcart) - [Products & Services](https://abclonal.com/catalog-antibodies?id=1) - [Publications](https://abclonal.com/learning/publications) - [Resources](https://abclonal.com/featured-topics) - [![](https://img.abclonal.com/abclonal/Public/Images/25121homepage-logo.png)](https://abclonal.com) - [Promotion](https://abclonal.com/sales/promos) - [Partnership](https://abclonal.com/partner/partnership) - [Company](https://abclonal.com/company/aboutUs) [\[fa icon="user"\]](https://abclonal.com/user/login) [\[fa icon="shopping-cart"\]](https://abclonal.com/shoppingcart) Blogs This is a search field with an auto-suggest feature attached. - There are no suggestions because the search field is empty. - [![Share on facebook](https://blog.abclonal.com/hs-fs/hubfs/hs_marketplace_assets/modules/Social%20Sharing/79/facebook-color.png?width=24&name=facebook-color.png)](http://www.facebook.com/share.php?u=https://blog.abclonal.com/blog/weekly-feature-lamin-antibody&utm_medium=social&utm_source=facebook) - [![Share on linkedin](https://blog.abclonal.com/hs-fs/hubfs/hs_marketplace_assets/modules/Social%20Sharing/79/linkedin-color.png?width=24&name=linkedin-color.png)](http://www.linkedin.com/shareArticle?mini=true&url=https://blog.abclonal.com/blog/weekly-feature-lamin-antibody&utm_medium=social&utm_source=linkedin) - [![Share on twitter](https://blog.abclonal.com/hs-fs/hubfs/hs_marketplace_assets/modules/Social%20Sharing/79/twitter-color.png?width=24&name=twitter-color.png)](https://twitter.com/intent/tweet?original_referer=https://blog.abclonal.com/blog/weekly-feature-lamin-antibody&utm_medium=social&utm_source=twitter&url=https://blog.abclonal.com/blog/weekly-feature-lamin-antibody&utm_medium=social&utm_source=twitter&source=tweetbutton&text=) - [![Share on google_plus](https://blog.abclonal.com/hs-fs/hubfs/hs_marketplace_assets/modules/Social%20Sharing/79/google_plus-color.png?width=24&name=google_plus-color.png)](https://plus.google.com/share?url=https://blog.abclonal.com/blog/weekly-feature-lamin-antibody&utm_medium=social&utm_source=google_plus) # Featured Product Weekly: Lamin Antibody [![Panyue (Penny) Hao](https://blog.abclonal.com/hubfs/Penny%20Hao.svg)](https://blog.abclonal.com/blog/author/panyue-penny-hao) [Panyue (Penny) Hao](https://blog.abclonal.com/blog/author/panyue-penny-hao) Jul 24, 2018 11:53:02 AM - [Tweet](https://twitter.com/share) [Nuclear lamina](https://www.ncbi.nlm.nih.gov/pubmed/12921235) is a layer of cross-linked fibrin network that commonly exists in higher eukaryotic cells. It is interior to the nuclear envelope with a fiber diameter of about 10 nm. The nuclear lamina of higher animals are usually composed of three intermediate filament polypeptides – lamins A, B, and C. The nuclear lamina is closely related to the stability of nuclear envelopes, maintenance of nuclear pore location, stabilizing interphase chromatin morphology and spatial structure, chromatin construction, and nuclear assembly. Lamins are a nuclear membrane structural component that are important for maintaining normal cellular functions such as [cell cycle regulation](https://www.ncbi.nlm.nih.gov/pubmed/24563346), [DNA replication](https://www.ncbi.nlm.nih.gov/pubmed/7911470), and [chromatin organization](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732390/). During [apoptosis](https://abclonal.com/research-area-pathway/apoptosis), lamin B1 (LMNB1) is cleaved by caspase; the replication of LMNB1 is associated with neurological diseases such as the pathogenesis of adult white matter dystrophy. In particular, LMNA/C phosphorylation at the Ser22 site is involved in mitosis and cell cycle processes. ABclonal Technology provides high-quality LMNB1, LMNA/C, and phosphorylated LMNA/C antibodies to aid in your research. ## LMNB1 Antibody The [KO-validated LMNB1 antibody](https://abclonal.com/catalog-antibodies/LMNB1PolyclonalAntibody/A1910) (A1910) can be used for WB, IHC, and IF. For a more cost-effective alternative, see [LMNB1 polyclonal antibody](https://abclonal.com/catalog-antibodies/LMNB1-Polyclonal-Antibody/A16685) (A16685), which can be used for WB and IF.  [![KO-validated LMNB1 antibody](https://blog.abclonal.com/hs-fs/hubfs/1910LMNB1.png?width=375&name=1910LMNB1.png)](https://abclonal.com/catalog-antibodies/LMNB1PolyclonalAntibody/A1910)[![LMNB1 antibody](https://blog.abclonal.com/hs-fs/hubfs/16685LMNB1.png?width=375&name=16685LMNB1.png)](https://abclonal.com/catalog-antibodies/LMNB1-Polyclonal-Antibody/A16685) ##               [![Get KO-validated LMNB1 Antibody](https://no-cache.hubspot.com/cta/default/2617944/d1ea5017-bcba-4ef0-9b47-ae68bdb343c4.png)](https://cta-redirect.hubspot.com/cta/redirect/2617944/d1ea5017-bcba-4ef0-9b47-ae68bdb343c4)                             [![See LMNA Antibody](https://no-cache.hubspot.com/cta/default/2617944/9f55797c-a691-47b9-b1cb-ced9f2ee4e72.png)](https://cta-redirect.hubspot.com/cta/redirect/2617944/9f55797c-a691-47b9-b1cb-ced9f2ee4e72) ## LMNA Antibody [![Lamin A Antibody](https://blog.abclonal.com/hs-fs/hubfs/0249LMNA.png?width=1844&name=0249LMNA.png)](https://abclonal.com/catalog-antibodies/LaminACPolyclonalAntibody/A0249) [![See LMNA Antibody](https://no-cache.hubspot.com/cta/default/2617944/9f55797c-a691-47b9-b1cb-ced9f2ee4e72.png)](https://cta-redirect.hubspot.com/cta/redirect/2617944/9f55797c-a691-47b9-b1cb-ced9f2ee4e72) ## LMNA/C Phosphorylated Antibody Duo [To battle the reproducibility problem in life science, ABclonal Technology provides phosphorylated antibody duos that include total protein antibodies and phosphorylated Lamin A/C antibodies.](https://abclonal.com/catalog-antibodies/phospho-lmna-s22-antibody-kit/RK04084) [![Phosphorylated lamin A/C antibody](https://blog.abclonal.com/hs-fs/hubfs/04084p-LMNAC-s22.jpg?width=250&name=04084p-LMNAC-s22.jpg)](https://abclonal.com/catalog-antibodies/phospho-lmna-s22-antibody-kit/RK04084)   [![Improve Your Data Validity](https://no-cache.hubspot.com/cta/default/2617944/4d8e3ea5-0e60-48dc-8ed0-8730ad13d367.png)](https://cta-redirect.hubspot.com/cta/redirect/2617944/4d8e3ea5-0e60-48dc-8ed0-8730ad13d367) Tags: [Antibodies](https://blog.abclonal.com/blog/topic/antibodies), [ABclonal News](https://blog.abclonal.com/blog/topic/abclonal-news), [Apoptosis](https://blog.abclonal.com/blog/topic/apoptosis), [Featured Product Weekly](https://blog.abclonal.com/blog/topic/featured-product-weekly) ![Panyue (Penny) Hao](https://blog.abclonal.com/hubfs/Penny%20Hao.svg) ### [Panyue (Penny) Hao](https://blog.abclonal.com/blog/author/panyue-penny-hao) Content creator, knowledge craver, all-around food fanatic thriving to survive in the fascinating yet uncharted world of biology. ## Related Posts [![necroptosis](https://blog.abclonal.com/hubfs/rsz_necroptosis.jpg)](https://blog.abclonal.com/blog/necroptosis-the-inflammatory-counterpart-of-good-ol-apoptosis) [Necroptosis: The Inflammatory Counterpart of Good Ol’ Apoptosis](https://blog.abclonal.com/blog/necroptosis-the-inflammatory-counterpart-of-good-ol-apoptosis) [![Programmed cell death, ferroptosis](https://blog.abclonal.com/hubfs/rsz_ferroptosis-blogcover.jpg)](https://blog.abclonal.com/blog/ferroptosis-as-a-new-type-of-inflammatory-programmed-cell-death) [Ferroptosis as a New Type of Inflammatory Programmed Cell Death](https://blog.abclonal.com/blog/ferroptosis-as-a-new-type-of-inflammatory-programmed-cell-death) [![](https://blog.abclonal.com/hubfs/Apoptosis%20Nuclear%20Lamina.png)](https://blog.abclonal.com/blog/get-with-the-programmed-cell-death) [Get With the Program(med Cell Death)!](https://blog.abclonal.com/blog/get-with-the-programmed-cell-death) ### Get the latest posts #### Products #### Services #### Support - [SARS-CoV-2](https://abclonal.com/sars_cov_2) - [SARS-CoV-2 IVD Raw Materials](https://abclonal.com/SARS-CoV-2-IVD-Raw-Materials) - [Molecular Biology Reagents](https://abclonal.com/molecular-biology/) - [Catalog Antibodies](https://abclonal.com/catalog-antibodies/) - [Catalog Proteins](https://abclonal.com/catalog-proteins/) - [NGS Lib Prep Kits](https://abclonal.com/ngs-lib-prep-kit/) - [ELISA Kits](https://abclonal.com/elisa-kits) - [Antibody Services](https://abclonal.com/antibody-services) - [Peptide Services](https://abclonal.com/peptide-services) - [Protein Services](https://abclonal.com/protein-services) - [Purchasing FAQs](https://abclonal.com/buying-faqs) - [Technical FAQs](https://abclonal.com/technical-faqs) - [Publications](http://abclonal.com/publications) - [Returns & Refunds](https://abclonal.com/returns-refunds/) #### [Contact Us](https://abclonal.com/contact-us/) - Phone: (888) 754-5670 - [Email: service@abclonal.com](mailto:service@abclonal.com) - Address: 500 W Cummings Park, Ste. 6500, Woburn, MA 01801, United States. 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