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Ferroptosis as a New Type of Inflammatory Programmed Cell Death

Posted by Bryent Lee on Nov 12, 2020 1:00:00 PM

When it comes to programmed cell death (PCD), apoptosis is usually the first process that comes to mind. However, there is a new type of inflammatory PCD discovered in 2012, known as ferroptosis, that is genetically and biochemically distinct from other PCD.1

 

Featured Product Weekly: AIFM1 Antibody

Posted by Panyue (Penny) Hao on Jul 31, 2018 12:58:57 PM

AIFM1, also known as Apoptosis Inducing Factor (AIF), is a widely expressed flavoprotein that plays an important role in caspase-independent apoptosis. AIF normally exists in the mitochondrial intermembrane space.

Featured Product Weekly: Lamin Antibody

Posted by Panyue (Penny) Hao on Jul 24, 2018 11:53:02 AM

Nuclear lamina is a layer of cross-linked fibrin network that commonly exists in higher eukaryotic cells. It is interior to the nuclear envelope with a fiber diameter of about 10 nm. The nuclear lamina of higher animals are usually composed of three intermediate filament polypeptides – lamins A, B, and C. The nuclear lamina is closely related to the stability of nuclear envelopes, maintenance of nuclear pore location, stabilizing interphase chromatin morphology and spatial structure, chromatin construction, and nuclear assembly.