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Autophagy: A Natural Detox

Posted by Kashyap Gayathri on Nov 18, 2020 3:00:00 PM

Autophagy can be understood as ‘self-eating’. In simple terms, it is a vitally important cleansing mechanism carried out by the cells in our body. It brings about the degradation of the cytoplasmic contents within membrane bound vesicles called lysosomes.

 

Ferroptosis as a New Type of Inflammatory Programmed Cell Death

Posted by Bryent Lee on Nov 12, 2020 1:00:00 PM

When it comes to programmed cell death (PCD), apoptosis is usually the first process that comes to mind. However, there is a new type of inflammatory PCD discovered in 2012, known as ferroptosis, that is genetically and biochemically distinct from other PCD.1

 

Antibodies Served With a Side of Phospho-Specificity

Posted by Kashyap Gayathri on Nov 11, 2020 12:00:00 PM

Anyone who is remotely interested in biology, or has perhaps scrolled through fitness websites to get in shape, has come across the word "protein". There is, however, much more to proteins than simply being a key player in maintaining active lifestyles. Proteins are ubiquitous in the cells of the body and are the driving force for key cellular processes. In order for proteins to carry out their duties, they need to be well-armed to execute their functions. This process of making the protein competent is achieved through specific post translational modifications (PTMs). The star of the PTMs is a cellular process called phosphorylation. The conventional methods adopted for quantifying phosphorylation are highly labor intensive. The development of phospho-specific antibodies has allowed for a huge sigh of relief from researchers due to their reputation of being quick, and detecting only phosphorylated forms of proteins in a complex mixture of phosphorylated and non-phosphorylated forms.

 

A Closer Look at the Fundamentals of Recombinant DNA Technology

Posted by Bryent Lee on Oct 27, 2020 4:09:38 PM

The advancement of recombinant DNA technology in recent years has drastically changed the world of research by controlling the expressions of target genes. Recombinant DNA combines genetic material from different sources, creating sequences that are unique and new to the genome. The DNA sequences used in the construction of recombinant DNA molecules can originate from any species, such as human, fungal, bacterial, and plants. 1

 

2020 Nobel Prize: Winners Announced for Award in Medicine

Posted by Dennis Miao on Oct 7, 2020 8:17:19 PM

This has been an incredibly exciting past few days in the world of scientific research. For those unfamiliar, the 2020 Nobel Prize winners are set to be announced this week; as of today’s writing on October 7th, 2020, three sets of award winners have already been unveiled in medicine, physics, and chemistry. Today, we’ll take a closer look at the backgrounds and distinguished research of the laureates in medicine.

 

FDA OKs Abbott's COVID-19 Rapid Test Kit

Posted by Dennis Miao on Sep 17, 2020 12:00:00 PM

In a press release on August 26th, 2020, Abbott Laboratories announced that they were issued an emergency use authorization (EUA) by the FDA for their new, rapid point-of-care COVID-19 antigen test. Branded as the “BinaxNOW COVID-19 Ag Card”, the test is unique compared to the more prevalent molecular-based detection tests for COVID-19 in that it utilizes a lateral flow assay, similar to traditional over-the-counter pregnancy tests. Contained in a portable, credit-card sized device, Abbott claims that the test can deliver results in as little as 15 minutes, representing a significant reduction in time compared to RT-PCR-based tests that have turnaround times on a scale of hours rather than minutes.