Jan 18, 2023 12:00:00 PM       by Kin Leung

Fun Science Breakthroughs Coming Back From Holiday

In the holiday rush, there were some fun science stories I was unable to get to other than the 2022 breakthrough of the year celebrating the ongoing JWST expedition. Now that we're back from celebrating with friends and family, let's check out some of what we missed!


Dec 19, 2022 11:32:20 AM       by Kin Leung

The Final Frontier: Science Breakthrough of the Year 2022

Every December, Science Magazine awards a scientific breakthrough of the year. When you take a look at the previous winning breakthroughs, they come from all different fields and many have been eventually awarded with Nobel Prizes. The breakthrough from last year, for example, is particularly important for structural biologists who hope to translate their findings into practical applications for other biologists and drug researchers. Since a breakthrough suggests a more recent discovery, it is no surprise that the Science Breakthrough of 2022 is the NASA JWST that has brought us myriad breath-taking images over the past year since its launch. 


Source: NASA

Dec 7, 2022 12:00:00 PM       by Kin Leung

The Ongoing Battle Against HIV and AIDS

December is a month of holidays and celebration, but it is also a time to raise awareness for a global epidemic that has lasted over four decades. During World HIV/AIDS Awareness Month, health organizations, including the United States Department of Veteran Affairs, serve to remind everyone about the importance of getting tested, to remember those who succumbed to the disease, and to improve access to advanced therapies.

Since its first identification and description in 1981, medical advances have offered effective therapies to keep the virus at bay, and in some cases even completely cure a patient of the human immunodeficiency virus, or HIV, and to prevent it from becoming the acquired immunodeficiency syndrome, or AIDS, which is often catastrophic to the patient. Unfortunately, as of 2021 per the World Health Organization (WHO), there are still over 38 million people living with HIV, with approximately 1.5 million new infections and 650,000 HIV-related deaths. Much of this has to do with lack of education or proper infrastructure and often obstacles to accessibility for treatment and prevention. I hope to explore HIV with you during this month of awareness so we can do our part to mitigate this persistent epidemic.

Nov 16, 2022 12:00:00 PM       by Kin Leung

Trim and Proper: A Nifty Method for Targeted Protein Degradation

A common experimental strategy in studying the effects of a specific protein in cells or organisms is to remove it. One can determine the physiological outcomes in the absence of that protein to ascertain its relative importance in maintaining normal functions, or in some cases, to note that it is dispensable or redundant and might have a backup within the cell to take up the slack. Some targeted techniques include RNA interference (RNAi) and CRISPR-based gene editing, and in many cases, it is possible to generate knockout cell lines or even organisms, like mice, that cannot express a specific protein. But when those strategies are not feasible for the experiment at hand, what is one to do?

Oct 17, 2022 12:00:00 PM       by Kin Leung

The Fungus Among Us: New Insights into the Tumor Mycobiome

As human beings with trillions of cells, each of which has their associated millions of copies of myriad proteins and other biological molecules, it’s something of a miracle that enough of the molecules bump together at the right times to keep us alive and functional. In addition to our own cells, we also coexist with microscopic neighbors, including various beneficial bacteria, while fending off pathogens like disease-causing bacteria, viruses, protozoans, and fungi. We often consider the bacteria and viruses in most human diseases, which invoke our immune systems to fight them to keep us healthy, but it also makes sense that the fungi can affect us as well, a topic in cancer research that is gaining attention.

Oct 5, 2022 7:57:29 AM       by Kin Leung

Celebrating the Sciences with the 2022 Nobel Prizes

As we try to come back to some level of normalcy after a couple of long, stressful years of pandemic, science has been continuing to chug along to improve the human condition. In celebration of this, we had silly achievements that made us laugh, then think, in the form of the Ig Nobel prizes, and this week, the cream of the crop was recognized with the three science Nobel Prizes. We wanted to highlight the Physiology and Medicine prize separately since ABclonal is a bioscience reagents company, but as we said before, every field of science is important to the pursuit of not just biological advancement, but the betterment of all humanity. So while you can also read about the achievements of the Medicine winner, Dr. Svante Pääbo, in the previous entry, here are the science prize winners in all the glory we can give them in this blog space!