Like most PhD students, I had to generate publications in order to earn my doctorate, and my mentor had to use those publications to support his grant applications. The ability to churn out publications in volume is critical to sustaining academic research, and the labs with the best reputations are the ones who regularly crank out quality articles that land in top-tier journals. However, does science have to be driven this way? Are we overlooking some great scientists or discoveries because they were unable to find the opportunities for funding and exposure, and thus dropped academia in search of another career? We should explore improving accessibility to funding and publication in research so that everyone has the chance to share their ideas.
Why Accessibility and Collaboration are Critical to Good Science
You may have stumbled upon many articles about the poor whales swallowing tons of plastic waste, flooding that is affecting communities and even national parks, or chemicals that are constantly threatening marine life. As the global temperature continues to increase, the ocean levels gradually rise, and life as we know it is threatened, it is almost like we are on our way to the apocalypse. However, humans do not have to accept this doomsday scenario! There are many things beyond our control that we will have to persuade our elected leaders to drastically change policies to conserve our natural resources, reduce pollution, and preserve biodiversity. But there are also many other things well within our control that we can do in the lab and at home to make a difference, since small actions will add up to significant positive change.
If you are reading this, either having earned your first faculty position or about to embark on leading a huge project, congratulations! You have obviously demonstrated the creative problem solving and other skills needed to successfully carry out and complete a scientific study…but maybe you’re not confident in your ability to lead or mentor? I would argue that many experiences you have accumulated up to this point will help you become the best mentor you can be, so let’s get to it as you cultivate the next generation of great researchers!
When I was in college, I enjoyed reading about Chindogu, which literally means “weird tool” in Japanese. The whole point of Chindogu was to make hilariously “unuseless” objects, somewhat like a tool that you might use, but wouldn’t actually buy because it was so absurd. An example of such absurdity is this Hay Fever Hat, and there are countless others that I would recommend you read and laugh about. Although Chindogu are essentially impractical devices meant for laughs, I got to thinking about how I MacGyver’d through graduate school in repurposing equipment and designing new ways to make my lab life easier even as our funding dwindled. Known affectionately as lab hacks, I’m sure you can find some of these on the internet, but I’ll share some of my favorites here.
5 Steps to a Better PCR: A Troubleshooting and Optimization Guide
Ever since Kary Mullis (that crazy guy, may he rest in peace) officially invented the polymerase chain reaction (PCR), an entire generation of molecular biology has exploded across the globe as scientists use PCR for a number of applications, from measuring gene expression to forensics. While the textbook technique is relatively simple, as I (and many other fellow researchers) can attest to from experience, producing an ideal PCR is far more challenging due to multiple factors.
Have you ever entered a lab where it looks like a disaster area? It may not have happened after an actual centrifuge accident or explosion, but you can tell that the lab needs a makeover in every sense of the word. Some cases are on the extreme end, such as this lab at Georgia Tech that was an unfortunate victim of negligence, but for the most part it may be just a messy neighbor who needs a gentle reminder to take a moment and clean up their bench for the greater good. (Figure 1)